产品货号:
Z27065
中文名称:
SLPI抗体
英文名称:
Anti-SLPI Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-SLPI Antibody |
指标别名 | ALP;MPI;ALK1;BLPI;HUSI;WAP4;WFDC4;HUSI-I;Antileukoproteinase;ALP |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | ELISA,WB,IHC |
基因名称 | SLPI |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | SLPI antibody was raised against a 17 amino acid synthetic peptide from near the center of human SLPI.The immunogen is located within amino acids 60 - 110 of SLPI. |
计算分子量 | 14kDa |
成分 | SLPI Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | SLPI Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Secretory leukocyte protease inhibitor (SLPI) is produced at mucosal surfaces,primarily the upper respiratory tract and is thought to play an important role in the antiprotease defense mechanism of the lung.SLPI forms inhibitory complexes with numerous proteolytic enzymes such as neutrophil elastase,and has been shown to possess anti-inflammatory,anti-viral,and antibacterial activities.Its expression in oral epithelial cells is stimulated by HIV-1 gp120,suggesting that SLPI is a component of the oral mucosal response to HIV-1.In peripheral blood monocytes,SLPI can inhibit NF-百B activation by inhibiting I百B degradation in the cytoplasm and competing for NF-百B binding sites in the nucleus.This attenuation of the inflammatory response may also act to suppress liver metastases and other cancer cell invasions,but promote blood-borne metastasis via an invasion-independent pathway. |
Uniprot ID | P03973 |
基因名全称 | Secretory leukocyte peptidase inhibitor |
蛋白名全称 | Secretory leukocyte peptidase inhibitor |
推荐稀释比 | SLPI antibody can be used for detection of SLPI by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 10μg/mL.Antibody validated:Western Blot in human samples and Immunohistochemistry in mouse samples.All other applications and species not yet tested. |
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